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The master and mistress of the renowned TCM family, Ai Zhen Hall, both met with misfortune, leaving their daughter Qin Zhi Ai to continue practicing medicine and saving lives. By chance, she treated the immortal puppet Meng Zong Zhu. Meng Zong Zhu, harboring a secret, came to the clinic to investigate the cause of Yun Shi's death. She used her status as an immortal puppet to control Little Doctor Xian, making herself his master. From then on, the two traveled together, practicing medicine and helping others, and became entangled in a series of court disputes. Ultimately, the truth behind Yun Shi's death was revealed, and Qin Zhi Ai successfully treated the emperor with her exceptional medical skills, earning the imperial title of "Little Doctor Xian."