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Roman (played by Dany Boon) is a medical consultant who is over forty years old, single, and has no romantic relationships. He has very little experience interacting with women due to his obsessive-compulsive disorder and fear of women. Dimitri (played by Kad Merad) is Roman's only friend and also a psychologist. Seeing Roman's "condition," Dimitri is deeply concerned and designs a complete "treatment plan" to help Roman lead a normal life. However, theseReform; Reconstruction; Renovation; Transformation plans not only fail to bring Roman back on track but also cause a series of humorous and troublesome situations. One day, a beautiful young woman named Anna (played by Alice Pol) appears in Roman's life, which might be his only chance to escape his single status. Will Roman seize this opportunity?