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At a small town on the border between China and Myanmar, a rebellious female student (played by Gao Ye) accidentally notices a new stranger (played by Yang Kun) after her dog becomes unusually agitated. The stranger is actually a professional hitman, and the student nearly falls into danger, but her brother, who is a drug enforcement officer (played by Zhang Mo), appears in time to stop the hitman. The drug enforcement officer arrests the hitman and accidentally discovers a major drug crimeClue, leading to the emergence of a major drug lord (played by Sun Honglei) and a decades-old unsolved case. A dentist (played by Ni Dahong) was inexplicably involved in a drug dealer's conflict, and in the chaos, a young girl was abducted by a young drug dealer. Now, a failed drug dealer, accompanied by the grown-up missing girl (played by Wang Luodan), returns to the small town in Yunnan for his last drug transaction. Police, drug dealers, hitmen, and the dentist's daughter are intertwined by fate, and a life-and-death struggle unfolds.