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Agent Gregorio (Antonio Banderas) and Ingrid (Carla Gugino) are two of the world's most elite spies. They meet during a mission and fall deeply in love, leading to the world losing two exceptional spies but gaining a happy family. Nine years later, the calm world is shaken again as Gregorio's former comrades begin disappearing mysteriously, indicating that conspirators are stirring up trouble once more. With no choice, Gregorio and Ingrid must re-enter the field, only to find themselves kidnapped as well! Now, the heavy responsibility falls on the shoulders of two young children, Carmen (Alexa Vega) and Junior (Daryl Sabara), who grew up in a spy family. Our spy prodigies are ready for action.